CORE LIST                            Complementary List                     Route of Administration 
                                                                                                               Pharmaceutical Forms and Strengths
3.0  A N T I - I N F E C T I V E S

3.1 ANTIBACTERIALS

3.1.1 Aminoglycosides 

           AMIKACIN                                                                Inj.:       50 mg/mL, 100 mg/mL, 125 mg/mL, 
                                                                                                                 and 250 mg/mL, 2 mL ampul/vial 
                                                                                                                 (IM, IV) (as sulfate) 
                                                                                                              100 mg, 250 mg and 500 mg vial (IM, 
                                                                                                                 IV) (as sulfate) 

          GENTAMICIN                                                            Inj.:       10 mg/mL, 1 mL ampul and 2 mL 
                                                                                                                  vial (IM, IV) (as sulfate) 
                                                                                                              40 mg/mL, 1 mL,  1.5 mLl and 2 mL 
                                                                                                                  ampul/vial (IM, IV) (as sulfate) 

                                  neomycin                                             Oral:     500 mg equivalent  to 350 mg base 
                                                                                                                  per tablet (as sulfate) 

                                 netilmicin                                             Inj.:       25 mg/mL and 50 mg/mL, 2 mL ampul
                                                                                                                  (IM, IV) (as sulfate) 
                                                                                                              100 mg/mL, 1.5 mL ampul and 2 mL 
                                                                                                                  vial (IM, IV) (as sulfate) 

3.1.2 Aminocyclitol 

                                 spectinomycin (2)                                  Inj.:     2 g vial (IM) 

3.1.3 Carbapenems 

                                imipenem + cilastatin (3)                      Inj.:    500 mg imipenem + 500 mg cilastatin 
                                                                                                                   per vial (IV infusion) (as sodium salt) 

                          Ú   meropenem (3)                                        Inj.:     500 mg and 1 g vial (IV) 

3.1.4 Cephalosporins 

First Generation

        CEFADROXIL                                                             Oral:     500 mg capsule (as monohydrate) 
                                                                                                            50 mg/mL granules/powder for 
                                                                                                                drops, 10 mL (as monohydrate) 
                                                                                                            250 mg/5 mL granules/powder for 
                                                                                                                suspension, 30 mL and 60 mL 
                                                                                                                (as monohydrate) 

         CEFAZOLIN                                                              Inj.:       500 mg and 1 g vial (IM, IV) 
                                                                                                                (as sodium salt) 

                             cefalexin                                                Oral:      250 mg and 500 mg capsule 
                                                                                                                (as monohydrate) 
                                                                                                            1 g tablet (as monohydrate) 
                                                                                                            100 mg/mL, granules/powder 
                                                                                                                for drops, 10 mL and 15 mL 
                                                                                                                (as monohydrate) 
                                                                                                            125 mg/5 mL granules/powder 
                                                                                                                for syrup/suspension, 30 mL 
                                                                                                                and 60 mL (as monohydrate) 
                                                                                                            250 mg/5 mL granules/powder for 
                                                                                                                syrup/suspension, 30 mL and 
                                                                                                                60 mL (as monohydrate) 

                                                               PNDF Vol. I, 5th ed. (2000)                                      - 12 -
         CORE LIST                            Complementary List                     Route of Administration 
                                                                                                               Pharmaceutical Forms and Strengths

Second Generation

        CEFOXITIN                                                                    Inj.:     1 g vial (IM, IV) (as sodium salt) 

                            cefuroxime                                                  Oral:    125 mg, 250 mg and 500 mg tablet 
                                                                                                                   (as axetil) 
                                                                                                              125 mg/5 mL granules for 
                                                                                                                   suspension, 50 mL, 70 mL 
                                                                                                                   and 100 mL (as axetil) 
                                                                                                             125 mg/sachet and 250 mg/sachet 
                                                                                                                   granules for suspension (as axetil) 
                                                                                                 Inj.:      250 mg and 750 mg vial (IM, IV) 
                                                                                                                  (as sodium salt) 
                                                                                                              1.5 g vial (IV infusion) (as sodium salt) 

Third Generation

       CEFTAZIDIME                                                              Inj.:       250 mg, 500 mg and 1 g vial 
                                                                                                                  (IM, IV) (as pentahydrate) 
                                                                                                              2 g vial (IV infusion) (as pentahydrate) 

       CEFTRIAXONE                                                             Inj.:       250 mg vial + 2 mL 1% solution of 
                                                                                                                  lidocaine (IM) (as disodium salt) 
                                                                                                              500 mg vial + 2 mL 1% solution of 
                                                                                                                  lidocaine (IM) (as disodium salt) 
                                                                                                              250 mg vial + 5 mL diluent (IV) 
                                                                                                                 (as disodium salt) 
                                                                                                              500 mg vial + 5 mL diluent (IV) 
                                                                                                                 (as disodium salt) 
                                                                                                              1 g vial + 3.5 mL 1% solution of 
                                                                                                                 lidocaine (IM) (as disodium salt) 
                                                                                                              1 g vial + 10 mL diluent (IV) 
                                                                                                                 (as disodium salt) 

       CEFOTAXIME                                                                Inj.:      250 mg vial + 2 mL diluent (IM, IV) 
                                                                                                                (as sodium salt) 
                                                                                                              500 mg vial + 2 mL diluent (IM, IV) 
                                                                                                                (as sodium salt) 
                                                                                                              1 g vial + 4 mL diluent (IM, IV) 
                                                                                                                (as sodium salt) 
                                                                                                              2 g vial + 10 mL diluent (IM, IV) 
                                                                                                                (as sodium salt) 

                              Ú cefixime                                                Oral:     100 mg and 200 mg capsule 
                                                                                                             20 mg/mL granules for drops 
                                                                                                                (suspension), 10 mL 
                                                                                                             100 mg/5 mL granules for 
                                                                                                                suspension, 30 mL and 60 mL 
                                                                                                             50 mg/g fine granules for 
                                                                                                                suspension, 1 g sachet 

Fourth  Generation

                              Úcefepime (3)                                            Inj.:     500 mg, 1 g and 2 g vial (IM, IV) 
                                                                                                                (as hydrochloride) 
 

 

                                                                  PNDF Vol. I, 5th ed. (2000)                             - 13 -
         CORE LIST                            Complementary List                     Route of Administration 
                                                                                                               Pharmaceutical Forms and Strengths

3.1.5 CHLORAMPHENICOL                                      Oral:      250 mg and 500 mg capsule 
                 (also for rickettsiae)                                                           125 mg/5 mL suspension, 30 mL 
                 (B)                                                                                              and 60 mL  (as palmitate) 
                                                                                                 Inj.:       1 g vial (IV; IM if recommended 
                                                                                                                     by manufacturer) 
                                                                                                                     (as sodium succinate) 

3.1.6  Glycopeptide 

                              vancomycin (3)                                       Inj.:       500 mg vial (IV) (as hydrochloride) 

3.1.7 Lincosamide 

                             clindamycin                                             Oral:      150 mg and 300 mg capsule 
                                                                                                                    (as hydrochloride) 
                                                                                                               75 mg/5 mL granules for suspension, 
                                                                                                                    30 mL, 60 mL and 120 mL 
                                                                                                                    (as palmitate hydrochloride) 
                                                                                                 Inj.:       150 mg/mL, 2 mL, 4 mL and 6 mL ampul 
                                                                                                                    (IM, IV)  (as phosphate) 

3.1.8  Macrolides 

          ERYTHROMYCIN                                                     Oral:       250 mg base tablet/capsule (B)
                (also for mycoplasma,                                                        250 mg and 500 mg tablet 
                chlamydiae)                                                                                 (as stearate) (B) 
                                                                                                              40 mg/mL granules/powder for drops 
                                                                                                                      (suspension), 30 mL  (B) 
                                                                                                                      (as ethyl succinate) 
                                                                                                              200 mg/5 mL granules/powder for 
                                                                                                                      suspension, 60 mL
                                                                                                                       (as ethyl succinate) (B) 
                                                                                                              400 mg/5 mL granules/powder for 
                                                                                                                       suspension, 50 mL and 60 mL 
                                                                                                                       (as ethyl succinate) (B) 
                                                                                                 Inj.:       500 mg vial (IV) (as lactobionate) 

                         clarithromycin                                             Oral:     250 mg and 500 mg base tablet 
                                                                                                              125 mg/5 mL granules/powder for 
                                                                                                                     suspension, 25 mL and 50 mL 
                                                                                                  Inj.:     50 mg/mL powder, 10 mL vial (IV) 

                     Ú  azithromycin                                               Oral:     250 mg capsule 
                                                                                                             200 mg/5 mL powder for suspension, 
                                                                                                                    15 mL and 30 mL 

3.1.9 Monobactam 

                         aztreonam (3)                                              Inj.:       500 mg and 1 g vial (IM) 

3.1.10 Nitroimidazole 

           METRONIDAZOLE                                                   Oral:      250 mg and 500 mg tablet 
                                                                                                               125 mg base/5 mL (200 mg/5 mL as 
                                                                                                                        benzoate) suspension, 30 mL 
                                                                                                                        and  60 mL 
                                                                                                  Inj.:       5 mg/mL, 20 mL ampul 
                                                                                                                        (pediatric IV infusion) 
                                                                                                                5 mg/mL, 100 mL vial (IV infusion) 
                                                                                                  Rectal:  1 g suppository 
 

                                                               PNDF Vol. I, 5th ed. (2000)                                         - 14 -
         CORE LIST                            Complementary List                     Route of Administration 
                                                                                                               Pharmaceutical Forms and Strengths

3.1.11 Penicillins 

          AMOXICILLIN                                                            Oral:      250 mg and 500 mg capsule 
                                                                                                                  (as trihydrate) 
                                                                                                               100 mg/mL granules/powder for 
                                                                                                                  drops (suspension), 10 mL and 
                                                                                                                  15 mL (as trihydrate) 
                                                                                                               125 mg/5 mL granules/powder for 
                                                                                                                   suspension, 30 mL and 60 mL 
                                                                                                                  (as trihydrate) 
                                                                                                                250 mg/5 mL granules/powder for 
                                                                                                                   suspension, 30 mL and 60 mL 
                                                                                                                   (as trihydrate) 

           AMPICILLIN                                                               Inj.:       125 mg, 250 mg, 500 mg, and 1 g 
                                                                                                                    vial (IM,IV) (as sodium salt) 

          CLOXACILLIN                                                             Oral:      250 mg and 500 mg capsule 
                                                                                                                    (as sodium salt) 
                                                                                                                 125 mg/5 mL powder for syrup/ 
                                                                                                                     suspension, 30 mL and 60 mL 
                                                                                                                      (as sodium salt) 
                                                                                                    Inj.:      500 mg vial (IM, IV)  ( as sodium salt) 

          OXACILLIN                                                                   Inj.:       250 mg and 500 mg vial (IM, IV) 
                                                                                                                       (as sodium salt) 

          PENICILLIN G BENZATHINE                                    Inj.:       1,200,000 units vial (LA) (IM) 
               (benzathine benzylpenicillin)                                             2,400,000 units vial (LA) (IM) 

          PENICILLIN G CRYSTALLINE                                   Inj.:       100,000 units vial (IM, IV) 
               (benzylpenicillin)                                                                        (as sodium  salt) 
                                                                                                                  200,000 units vial (IM, IV) 
                                                                                                                        (as sodium  salt) 
                                                                                                                  500,000 units vial (IM, IV) 
                                                                                                                        (as sodium  salt) 
                                                                                                                 1,000,000 units vial (IM, IV) 
                                                                                                                        (as sodium  salt) 
                                                                                                                 5,000,000 units vial (IM, IV) 
                                                                                                                        (as sodium  salt) 

           PENICILLIN G PROCAINE                                      Inj.:       300,000 units procaine pen. G + 
                (procaine benzylpenicillin)                                                     100,000 units buffered pen. G 
                                                                                                                       sodium per vial (IM) 

           PHENOXYMETHYLPENICILLIN                             Oral:      250 mg and 500 mg tablet/capsule 
                              (penicillin V)                                                                 (as potassium salt)
                                                                                                                 50,000 units/mL granules/powder 
                                                                                                                        for drops (syrup/suspension) 
                                                                                                                 15 mL and 30 mL (as potassium 
                                                                                                                        salt) 
                                                                                                                 125 mg/5 mL granules/powder for 
                                                                                                                        syrup/suspension, 30 mL and 
                                                                                                                 60 mL (as potassium salt) 
                                                                                                                 250 mg/5 mL granules/powder for 
                                                                                                                        syrup/suspension, 30 mL and 
                                                                                                                 60 mL (as potassium salt) 
 

                                                              PNDF Vol. I, 5th ed. (2000)                             - 15 -
         CORE LIST                            Complementary List                     Route of Administration 
                                                                                                               Pharmaceutical Forms and Strengths

                            ampicillin + sulbactam                              Inj.:       250 mg ampicillin + 125 mg sulbactam 
                                                                                                                     (as sodium salt) per vial  (IM, IV) 
                                                                                                                  500 mg ampicillin + 250 mg sulbactam 
                                                                                                                     (as sodium salt) per vial (IM, IV) 

                           co-amoxiclav                                                Oral:      250 mg amoxicillin (as trihydrate)  + 
                         &n